
综合疗法

The Cyprus Protocol – Multimodal Combination Therapy for Long COVID, Post-Vac and Chronic Illnesses
In the field of HIV and cancer, combination therapy is one of the most successful forms of treatment – often it is the gold standard in the specific field.
我们与世界各地的贡献者一起,通过我们的临床经验和以患者为主导的研究,开发出了首个针对长 COVID、真空后综合症和慢性疾病的多模式综合疗法方案。
We named it after it’s place of origin:
塞浦路斯议定书
Below you find a dynamic list of the protocol’s elements and a treatment schedule example.
我们治疗的疾病

我们在血液透析中心采用塞浦路斯方案治疗哪些疾病?
以下是我们诊所治疗的最常见疾病的几个例子(不限于此):
- 朗科维德(PCS)
- 抽吸后(PVS)
- 感染后/病毒后综合征
- POTS
- EDS
- MCAS / IBS / SIBO
- PANS / PANDAS
- PIMS / MIS-C
- 自体免疫疾病
- 慢性疲劳综合征
- 再活化病症(EBV、单核细胞增多症、巨细胞病毒、疱疹、巴贝丝菌、巴顿氏菌)
- 莱姆病
- 纤维肌痛
- ME/CFS
- 多发性硬化症
- 狼疮
- 类风湿性关节炎
- Sjögrens 综合症
- Raynaud’s Disease
- 硬皮病
- 老年痴呆症
- 帕金森
- SFN / 神经病变
- 监控监
- 其他存在炎症、自身免疫和微循环问题的病症,以及根源在于毒素或病原体的病症
塞浦路斯议定书》要点
点击《塞浦路斯议定书》各要素,了解更多详情
对于每一位患者,方案都需要因人而异。
With the new diagnostic tools of our D-T-R model – Continous Diagnostics we are now able to apply targeted treatments with higher precision.
Independent of the treatment a patient is undergoing – without adapted nutrition for the three treatment phases pre-treatment, on-treatment and post-treatment, the achievable results differ.
This is why we base our Combination Therapy on individual and personalized nutrition plans for every patient, based on the results of blood panel test and food intolerance test that show IgG reactions to 287 foods (vegetables, fish & seafood, fruits, spices, nuts, legumes, meat, egg & milk, cereals & seeds, nuts, coffee & tea and novel foods).
Our Clinical Nutritionist Chryso Zorbas will hold your hand nutritionally from day one and guide you along the therapy with a personalized diet plan that will enhance your recovery process. Needless to say that our Health Coaching (see below) is a perfect match and goes hand in hand with our Clinical Nutrition Supervision.
Learn more about Clinical Nutrition Supervision here
Chronic Illness is very complex – having an expert patient turned professional Health Coach by your side throughout your whole journey offers priceless knowlege and guidance.
Our Health Coach Tanja Walser will coach you from day one and guide you along the therapy with a personalized coaching plan that will include all the dos and don’ts and give you a headstart despite brainfog, anxiety or other symptoms you are battling with.
Learn more about Health Coaching here
Our most effective treatments to date: At the core of our multimodal Combination Therapy are several forms of Therapeutic Apheresis’ – special blood purifications by precipitation/adsorption/filtration procedures. They serve to treat microcirculation / blood flow issues (microclots are removed, blood flow increased) and removes pathogenic or disease-sustaining proteins as well as protein-bound substances and autoantibodies from the blood. Amongst other substances environmental toxins, inflammation proteins, viral spike protein, cholesterol + autoantibodies are removed
Learn more about H.E.L.P. Apheresis
Learn more about Inuspheresis®
Learn more about Immunoadsorption
In some cases H.E.L.P. Apheresis will be combined with TPPE – Therapeutic Partial Plasma Exchange
Heckel HT3000 全身热疗系统可以有针对性地提高人体核心温度,从轻微发热到高烧不等。全身热疗不仅能解决症状,还能在整个机体内重建更好的调节控制。从促进健康、减轻疼痛到慢性病和癌症的辅助治疗,海克尔全身热疗系统为治疗各种疾病和病症做出了重要贡献。在 Long Covid 和 Post Vac 中,释放受体和分解致病蛋白是进一步的预期效果。
Long Covid and many other Chronic Illnesses are at their root an endothelitis/vasculitis with severe inflammation, combined with hypercoagulation and often viral persistence. Autoimmunity components can be involved too.
IV treatments work directly where needed the most: in the blood vessels in the desired concentration.
IV/Intravenous therapies that are used in our Long COVID and Chronic Illnesses Combination Therapy are:
– IV Vitamin C (Reducing inflammation)
– IV Glutathione (Antioxidant)
– IV Multivitamin Protocol (Balancing deficiencies)
– IV NAD+ (Metabolism/mitochondria benefits)
– IV Alpha Lipoic Acid (Metabolism/nerve pain reduction)
– IV Zinc (Reducing inflammation, speeding up recovery)
– IV Magnesium (Electrolyte reducing fatigue and anxiety)
– IV NAC (Reduces brainfog/relieves respiratory discomfort)
– IV Taurin (Is Cytoprotective (cell protective) and detoxyfying)
– IV Arginine (Increases elasticity of blood vessels and increases blood flow)
– IV Lysine (Increases cell healing and wound healing)
– Other IVs: Iron, Selenium, Amino Acids, Minerals and more
Peptide Therapy:
Peptide therapy offers a groundbreaking approach to restoring balance and vitality for individuals struggling with long COVID, post-vaccine syndrome, and chronic illnesses. Peptides are short chains of amino acids that act as signaling molecules in the body, promoting tissue repair, immune modulation, and cellular rejuvenation. By targeting underlying dysfunctions such as inflammation, impaired immunity, and mitochondrial damage, peptide therapy can accelerate recovery, enhance energy, and support overall wellness. Tailored to each patient’s unique needs, this therapy provides a safe and effective way to improve quality of life, fostering the body’s natural ability to heal and thrive.
Find more information on our IV Therapy and Peptide Therapy click here for iv therapy and peptide therapy
Chelation Therapy:
Chelation therapy is a medical intervention characterized by the administration of chelating agents, substances with a high affinity for certain metal ions, to facilitate the removal of heavy metals and minerals from the body.
Find more information on Chelation Therapy here
Our Nutraceutical treatment strategy for the detoxification from viral spike protein involves the following 4-step process:
The first step is preventing reinfection by blocking the receptors on host cells, which the virus and viral spike protein use to gain entry.
The second step is to help restore autophagy processes, which are the body’s natural way of cleaning out damaged cells and regenerating new ones.
The third step aids in liberating viruses and viral spike proteins by selectively targeting infected or transfected cells.
The fourth step facilitates the sequestration of viral spike protein and virus, effectively removing them. The most efficient way to do this is H.E.L.P. Apheresis and where that is not possible, the use of Algerol is indicated.
This comprehensive approach aims to remove the spike protein from the body safely while also enhancing the immune system’s ability to prevent further infections.
At the end of our therapy course we add a 3-6 months NAC Augmented protocol.
Find more about Nutraceutical Therapy here
Medication and supplement protocols increase H.E.L.P. Apheresis results further and can be used to treat patients symptom-specific. The protocols include Antiviral Protocols and Anticoagulation Protocols.
Symptoms the medication protocols focus on are:
– Viral persistence
– Persisting hyper coagulation
– MCAS (mastcell activation syndrome), often combined with gastroparesis
– Endothelial damage, often combined with hypercholesterolaemia
– Neuro inflammation/brain inflammation
– Fatigue, PEM often combined with mitochondrial dysfunction
– Insomnia
– Induced anxiety/paranoia/depression
– Reactivated viruses
– Others
Find more information on Antiviral Therapy and Anticoagulation Therapy
Anxiety, Depression, PTSD, Chronic Pain and Fatigue Therapy for Long Covid and Chronic Illness
Are you or a loved one struggling with the lingering effects of Long Covid or battling the relentless challenges of chronic illness? At the Apheresis Center we understand the toll these conditions can take on both your physical and mental well-being. That’s why we offer revolutionary approaches to treatment.
Find more about Depression & Anxiety Therapy here
Colon Hydrotherapy, also known as colonic irrigation, constitutes an internal cleansing procedure designed to rid the colon of deleterious waste materials. This therapeutic intervention serves as a rapid and highly efficient means of detoxification for the body. The mild internal hydration expeditiously eliminates pathogenic toxins by leveraging the natural peristaltic movements, further facilitated by abdominal massage. Notably, this process has implications for individuals with symptoms that present similar to Mast Cell Activation Syndrome (MCAS), as it influence the systemic responses associated with this symptoms often triggered by Long Covid, Post Vac or other Chronic Illnesses.
Our Medical Team has designed a MCAS treatment package which is tailored to each patient individually
MCAS Blood Test (CCL2, IL-6, IL-8, IL-31, IL-33, TNF-alpha, Tryptase)
Nutrition Plan
3x Colon Hydrotherapy, ozonated treatment
3x Leaky Gut IV (L-Lysin, Taurin, L-Alanyl-Glutamin, Glycin, Cholinchlorid, Magnesiumchlorid, Kaliumchlorid
MCAS Medication Plan including Nutraceuticals and Nanozeolites
Find more information on Colon Hydrotherapy and MCAS Treatment here
The application of Intravenous Immunoglobulin (IVIG, if subcutaneously administered also called SCIG)) and monoclonal antibodies (mABs) like Evusheld or Xevudy (Sotrovimab) represents a new area in treating Long Covid, Post Vac and Chronic Illnesses. These conditions involve complex immune dysregulation and inflammatory responses. IVIG is a concentrated preparation of immunoglobulins derived from pooled human plasma.
Monoclonal antibodies, designed to target specific components of the immune response, present another avenue for intervention. Both IVIG and mABs are being investigated for their potential to restore immune homeostasis.
The current official indications include symptoms present in chronic illness and many post-viral conditions: Myo- and Pericarditis, Small Fiber Neuropathy but also acute/severe conditions like Sepsis.
Find more about IVIG and mABs Therapy here
For specific symptoms and subgroups after H.E.L.P. Apheresis treatment these treatments can speed up and enforce the recovery process. (Note: HBOT is only administered after H.E.L.P. Apheresis therapy. Ozone-EBOO is only administered after H.E.L.P. Apheresis and only in special cases)
Find more information on Hyperbaric Oxygen Treatment here and Cryotherapy here
Mitochondrial therapy, also known as metabolic correction, is an emerging approach in the management of Long Covid and chronic illnesses characterized by fatigue. This therapy aims to enhance mitochondrial function, which is often impaired in these conditions, by providing specific nutrients and cofactors that support cellular energy production. Key substances used in mitochondrial therapy include NAC (N-Acetyl L-Cysteine), L-Serine, L-Carnitine, Nicotinamide Riboside (NR), L-Choline, NT Factor, and NADH. These compounds work synergistically to replenish depleted cellular antioxidants, enhance mitochondrial biogenesis, improve fatty acid metabolism, and restore ATP production, ultimately helping to alleviate fatigue and improve overall cellular health in individuals suffering from prolonged symptoms of Long Covid and other chronic fatigue-related conditions.
Find more about Mitochondrial Therapy here
Many of our last year’s patients had to come back to us for another course of H.E.L.P. Apheresis and Combination Therapy treatment, because they reinfected with Covid and were thrown back to experiencing Long Covid symptoms. This is why we started giving out ‘Early Treatment packages’ which avoid exactly that. Our prescribing doctors will supply you with everything needed to get through your next reinfection without risking to worsen again.
治疗时间表示例
塞浦路斯议定书》治疗方案的可视化
In the below PDF you find a visualisation of available treatments (this is solely for the purpose of demonstrating available options – this NOT a real life case/treatment schedule)
推荐:下载并放大查看详情。
有关治疗性血液透析用于治疗长病程/ Vac 后及其他病症的科学来源和研究
H.E.L.P. 血液透析
A collection of sources which have published success rates can be found at the Long Covid Apheresis Community (LCA Community): https://lcacommunity.org/research
LCA 社区公布的结果已在 ISFA2023 上得到确认:
非球面
Science 2024 – new study looking at the relation between microclots and immune damage in Long Covid:
Quote: ‘…coagulation in Long Covid is indicated by the detection of circulating fibrinolysis-resistant microclots that are enriched in vWF, C7, acute-phase serum amyloid proteins, and fibrin, proteins identified in the proteomics screen by Cervia-Hasler et al. as contributors to Long Covid.’
Full study: https://www.science.org/doi/10.1126/science.adn1077
简单地说,这项研究调查了一些人从 COVID-19 (一种被称为 "长 Covid "的疾病)康复后症状持续存在的原因。研究人员发现,Long Covid 患者的免疫系统,特别是补体系统持续激活,导致炎症和血凝块形成。与急性 COVID-19 不同的是,肝脏在免疫反应中扮演着重要角色,而在 Long Covid 中,炎症似乎更加局部化,涉及组织和免疫细胞。研究表明,这种持续的免疫激活,尤其是补体系统的激活,是导致朗科维德患者出现症状的原因之一。
研究人员发现了与 Long Covid 相关的特定蛋白质,如 pentraxin 3 和补体成分。补体系统一旦失控,就会对细胞和血管造成损害。在 Long Covid 患者中,有证据表明补体激活过度,导致炎症和microclot 的形成。这种持续的炎症状态,即使在没有广泛的血液凝结的情况下,也能解释朗科维德所观察到的挥之不去的症状,如疲劳和认知问题。
此外,研究还发现了与凝血有关的因子失衡,这表明Long Covid的血栓性炎症存在潜在机制。虽然还不完全清楚 Long Covid 中持续免疫激活和凝血的确切原因,但这项研究表明,针对免疫和凝血系统的特定成分可能是治疗 Long Covid 的一个潜在途径。
H.E.L.P. Apheresis and Inuspheresis® address most if not all of the above. Microclots, Hypercoagulation, Inflammation, Pathogens to list just a few modes of action of H.E.L.P. Apheresis and Inuspheresis® . The rest can be addressed by other elements of the multimodal Combination Therapy of ‘The Cyprus Protocol’.
You will find extensive information on our blog post about different types of Apheresis and which type is suitable for which purpose HERE
E-mail info@apheresiscenter.eu
Call us +357 24257400
我们的穿刺中心和H.E.L.P. 穿刺上电视
ITV News、BBC News、France 2 和 WDR TV。摘录部分有关我们的无细胞疗法中心和H.E.L.P. 无细胞疗法治疗后/长胞病毒、后真空综合症和慢性疾病的报道。
客户感言
杰里米-史密斯,美国长科维德
‘I had 4 Help Apheresis treatments last year in Germany. They brought me back to 80% of my former capacity.
The Apheresis Center is a totally different experience and I am super happy I chose Cyprus. It is very different from Germany. The doctors, nurses and the whole team are doing everything to bring me back to my full capacity, their knowledge about Long Covid and the individually adapted treatment is great – a real concierge medicine experience! I missed home last year in Germany – here in Cyprus not a single day, we even extended our stay and will come back next year for holidays!’
You can read and watch Jeremy’s full story here: Full Video
卡特里娜-克鲁拉,美国长科维德
‘I have had some amazing results with H.E.L.P. Apheresis for my Long Covid – my 6th treatment got me back to feeling 75% to 90% recovered. Larnaca was truly an amazing place for recovery. Also the great community for support that formed with others getting treatment was so wonderful. It was so nice to have a team of people helping you that “got it” and believed you in addition to being with others suffering the same life changing illness.’
帕特里夏-普莱斯,ME/CFS,英国
帕特里夏自 2015 年以来一直患有严重的 MECFS:
‘My Help Apheresis treatment improved my ME by 80%. Help Apheresis took me from being mostly bed bound 23 hours a day – I could not be upright without my heart jumping to 170 beats per minute, even higher if I tried to have a shower – to being able to be upright and be mobile almost every day. It changed my life! I can now manage my own life again. I can go outside again and I was able to gain weight and can now eat three solid meals a day again!
You can watch Patricia’s full story here: Full Video
兰登-威廉姆斯,美国长科维德
在我们使用H.E.L.P. Apheresis 治疗之前,Landen 一直在呼吸、焦虑、脑雾和其他症状中挣扎。治疗几个月后,他现在已经恢复到以前的 70%,有些疲劳和 PEM 是最后部分持续存在的症状。他正在接受综合疗法治疗。以上视频是他在 1819 新闻节目中的简短发言/摘录(来源:1819 新闻)
Combination Therapy and H.E.L.P. Apheresis do not achieve the same results in the same time frame for different patients. From our clinical experience we have seen similar success rates as presented on the ISFA 2023 (World Conference of the International Society for Apheresis) – 80% success rate with results varying from smaller improvements to being fully curative. The majority of patients saw a significant improvement. Long Covid, Post Vac and CI are umbrella terms with different subsets – no patient presents the exact same symptoms set.
The time frame in which patients see results also vastly differs – from first treatment to several months.
ARTE 电视纪录片 "Long Covid - 塞浦路斯的愈合
ARTE TV Documentary ‘Long Covid – Healing in Cyprus’ about our Apheresis Center
The documentary aired in June 2024. A team of journalists from European TV channel ARTE TV accompanied three of our Long Covid and Post Vac Syndrom patients and interviewed them and our team at the Apheresis Center. Here you can watch an excerpt of the documentary which is also easy to watch for patients with cognitive dysfunction, brainfog and related migraines. English audio by Dubly.
Since the documentary was filmed, new scientific findings have been made, you can find the latest studies published here.
Markus has published a blog post here, where he describes the developments and updates since the documentary was filmed.